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The Original Liquid Collagen.
Lose weight while you sleep!

 What is Calorad?
How does it work?

The role of Calorad
Suggestions for use

History of Calorad

3 Studies
Calorad Testimonials
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What is Calorad?

Calorad Bovine Formula is a very high quality liquid collagen. Calorad was the first to introduce the concept of an oral liquid collagen. "Lose weight while you sleep!" Calorad Bovine Formula continues to be taken by those in the health care field as well as tens of thousands of others.


"The Original" Liquid Collagen CALORAD with the motto..."Lose weight while you sleep!" Helps rebuild muscle and support the repair of skin, hair and nails. "A very healthy food component!" It is simple to use - you take a tablespoon of Calorad® just before you go to sleep and live your normal life. That's it.


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Click to buy now Calorad Bovine Formula - "The Original" Liquid Collagen - bottle 500ml


How does Calorad Bovine Formula work?

30-Year Sleep Researcher Talks about Calorad...


Dr. John Zimmerman has a Ph.D. in Biological Psychology and Neuroscience.  He has been involved with sleep research for over 30 years.


"My name is Dr. John Zimmerman.  I'm the director of one sleep lab in Reno and the owner of another sleep lab in Carson City, both in northern Nevada.  I've been in the field of sleep disorders and electrophysiology for over 30 years. 


There is an aspect of the delivery system of Calorad, which is very important with respect to the body's natural anabolic processes.  Taking a very high protein product in the form of liquid collagen prior to sleep onset allows the body to access the food at just the right time.  During the first 90 minutes of sleep for a normal individual (who does not have a sleep disorder), a person gets the deepest sleep and the longest duration of that sleep. 


The deepest sleep stages at night are called stages 3 and 4 sleep.  Stage 3 sleep I refer to as "deep sleep" and stage 4 sleep I call "very deep sleep."  They are composed of different amounts of a brain wave called "delta."  During the day our brainwave patterns are mostly composed of "alpha" when we are relaxed with our eyes closed and "beta" when the eyes are open.  Beta also occurs when we're thinking, speaking, listening, or looking at things.  The frequency of beta is around 15-30 cycles per second or Hertz (Hz).  When we relax and close our eyes, particularly if we are not thinking of anything, our brainwaves change to "alpha", which have a frequency of around 8-12 or 13 cycles per second. 


What is associated with sleep are two other brainwaves: theta and delta.  Theta, which is 4-7 Hz, occurs during "light sleep" (stage 1) and "medium sleep" (stage 2).  Delta occupies frequency range 0.5-2 or 3 cycles per second.  Varying amounts of delta activity define the differences between stage 3 and 4 sleep.  


When we first enter into sleep, we go into stage 1 sleep for a few short minutes, then stage 2, and then proceed directly to stages 3 and 4 (assuming normal sleep patterns).  Descent into sleep is like a staircase downward: stage 1, stage 2, stage 3, stage 4, light sleep, medium sleep, deep sleep, very deep sleep.  After 80-90 minutes, we re-ascend the sleep staircase, climbing back up from stages 4, 3, 2, etc.  then we enter a special sleeping state called REM, short for rapid eye movement, sleep, when we dream.  


The first sleep period (of 4 or 5) of the night occurs during the first 90 minutes.  It has the largest amount of deep sleep and this is very important to the release of a growth hormone that our bodies use for rejuvenation and repair.   The second sleep period has less deep sleep.  The third sleep period would usually have no or very little deep sleep and relatively little stage 3 sleep and hence very little growth hormone release.  By the time a person gets to the fourth sleep period around 4-5 a.m. in the morning, there is usually no stage 3 or 4 deep sleep at all (and growth hormone release has all but ceased).  All your remaining sleep will consist of stages 1, 2 and REM, with increasingly longer REM periods (and more intense dreams!) towards the end of the night.  


During stages 3 and 4 of deep sleep, "we release growth hormone from the pituitary gland into the blood stream.  Growth hormone has the beneficial effects of building up lean muscle mass and burning fat!"  If we provide the body with a high amount of protein near the time it produces growth hormone, it will utilize it very effectively.   


 There is also another factor to be considered from a nutritional standpoint called "specific dynamic action" (SDA).  The SDA is different for the three food groups: fats, carbohydrates, and proteins.  Proteins require the most amount of work to digest and consume the most amount of calories during this process.  This is because proteins have to be uncoupled into separate amino acids.  You can think of a protein as either a long string of beads or a long line of box cars in a train that have to be uncoupled in individual beads or individual box cars.  Proteins have to be broken down into short poly peptides or free amino acids before they can be absorbed by the intestinal villi into the bloodstream.  The energy to adjust proteins (break them down into free amino acids), requires the expenditure of calories.  "This is why it is most beneficial to provide the body with a very high protein food at the particular time of the 24 hour day when we’re most likely to be utilizing our anabolic processes" - during stages 3 and 4 sleep - when growth hormone is released into the blood.

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The role of Collagen


Calorad® in muscular development and total well being

By John H. Norris, M.D., Ph.D. and Reginald D. Barnes, Jr., M.D.


Calorad® is a specially formulated collagen product designed by Michel Grisé, which when used as directed, can result in significant fat loss, an increase in lean body muscular mass and increased well being, as demonstrated in clinical trials conducted over a period of several months.


In human physiology, it is well known that muscle and adipose (fat) tissue metabolism are influenced directly by the complex interplay between insulin, exercise, glucocorticoid (stress hormones), growth hormone (GH), amino acids (including arginine and leucine), proteins, L-hydroxyproline, fats and other substances. Calorad® appears to augment known physiological processes in the metabolism of fat and muscle, which might explain its success as discussed below.


Little if any fat catabolism (fat burning) can take place in the presence of high insulin levels such as those found in, but not limited to, type two diabetes mellitus with insulin resistance or, most commonly, after eating a meal high in carbohydrates or fat. Insulin levels are lowest during fasting.


When Calorad® is used as directed after three to four hour fast prior to going to bed, the subject has extended the hours of fasting significantly in addition to that which occurs during sleep. This results in longer periods of low insulin levels, allowing more time for fatty acid metabolism and resultant fat loss.   GH is one of several significant hormones involved in muscular development and it is secreted episodically 24 hours daily. Synthetic growth hormones are often abused by body builders attempting to produce muscular hypertrophy (increased muscular size). Patients with low growth hormone levels often have little muscle mass and/or tone. The most consistent period of GH secretion in both children and young adults (and possibly other age groups), is within the onset of the first slow wave sleep (deep sleep). Delay in the onset of the deep sleep usually results in the delay in the onset of the major GH peak.


GH levels are highest during slow wave sleep and lowest during rapid eye movement (REM) sleep. Furthermore, GH secretion is augmented during fasting. Preliminary studies of Calorad® - collagen suggest a significant deepening in all levels of sleep. This might allow for an increased net secretion of growth hormone and an increase in muscular mass. What’s more, this deeper sleep might account for the subjective feeling of "improved well being" described in many subjects using Calorad®.


Protein, amino acids, L-hydroxyproline, and other building blocks of muscle and collagen are essential for muscle rebuilding. During rest, a complex interplay takes place as muscle and cartilage repair under the influence of GH. If one is deficient in any one of these building blocks necessary for muscle rebuilding, those building blocks will be removed from a healthy muscle (catabolism). Furthermore, certain amino acids, particularly arginine and leucine, stimulate GH secretion. When subjects take Calorad®, this catabolic process is felt to be limited because Calorad® is rich in the amino acids and the collagen building blocks necessary for muscle and cartilage growth, thus resulting in a net increase in lean body mass. At present, studies are being designed to measure GH and insulin levels during sleep in subjects using Calorad® versus matched controls.

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Click to buy now Calorad - "The Original" Liquid Collagen - bottle 500ml


Suggestions for use:

  • Lose weight while you sleep!

  • "A very healthy food component!" It is simple to use - you take a tablespoon of Calorad® just before you go to sleep and live your normal life. That's it.

  • Take a tablespoon of Calorad® with eight ounces of water right at sleep time, just before hitting the pillow and closing your eyes. Not that you stay up, read, TV, etc.

  • You should have an empty stomach, which means no solid food for at least three hours before taking Calorad®. No liquids for at least two hours prior to bedtime except for water that can be taken anytime.

  • If you have eaten late and do not wish to stay up the minimum three hours, it is suggested that you take Calorad® on the next morning when waking up and not eat for at least 30-45 minutes after taking it.

  • The reason for the empty stomach is to help insure that Calorad® go as efficiently as possible into the bloodstream as opposed to going through the intestinal system, thereby not getting the best benefit, i.e. “good assimilation.”

While there are no medical contraindications with taking Calorad®, here are a couple of points that will be beneficial for you to know:

  • If there should be a yeast condition in the body, sometimes it can minimize the beneficial result of Calorad®. It should be cared for (Agrisept® could help).

  • It is very important that water be taken in. It would be a good goal to make sure that a minimum of 8 glasses of water be taken a day. This is important whether or not Calorad® is being used.

  • A person having a thyroid condition should be aware of it. If not on medication, in order to realize the intended benefits of Calorad® it might be best to consult a doctor and to determine as to whether they should be on a medication for it or not.

  • The bowels should be clean to ensure good assimilation of any nutrition that one takes. Sometimes a good colon cleanse is in order.

  • The intake of excessive amounts of carbohydrates can minimize the benefit of Calorad®.

  • Be fully committed to the program for at least 3-6 months and “try your best” to live a balanced life and make sure to weigh and measure yourself at the start!

If you have questions feel free to contact us.

Order Calorad Bovine Formula today On Sale! Save today at Introductory Prices!

Click to buy now Calorad - "The Original" Liquid Collagen - bottle 500ml





We are all facing it. It's been over 20 years since the fitness revolution began. We spend over $40 billion a year on weight loss and fitness, all to look and feel good.



We are losing the battle. Many of us are overweight, tired and sluggish. Most diets don't work and we can't stick to an exercise program. The extra fat we carry around is really stored energy, but we seem to be unable to utilize it without creating health problems.


More and more studies are confirming that excess weight is a problem the world over. With aging populations, the threat to our health is greater than ever before! 



First, it's not our fault. The world has changed and we must adapt. Our bodies were made to expend more calories throughout the day. Modern technology and our new, more sedentary lifestyles have created this dilemma. Now modern technology, along with Mother Nature, has given us an alternative. 



When you lose fat and inches, you look great, feel great and have more vitality. Calorad® assists the body in utilizing unwanted fat, thereby allowing us to lead a more robust and healthy lifestyle*. This all-natural collagen-based drink may change your life. Thousands of people, including many health care professionals, are using Calorad® and looking better than ever before. Doctors are advising their patients and clients to try Calorad® as a safe alternative that may help them to look and feel better.



It Isn't!



Some twenty years ago, Michel Grisé, a brilliant Canadian formulator, was asked by a veterinarian friend to formulate a product that would eliminate "fatty liver syndrome" in poultry (fat chickens stop laying eggs). Within days, the excess fat was eliminated and the chickens and the farmers were happy.



That's where the really great news begins. Due to the dramatic success of the product, Michel decided to reformulate it for people, naming it "Calorad®." Michel tested it on himself and shared the positive results with us. That was over 20 years ago! Since then, hundreds of thousands of people have achieved dramatic results by using Calorad®. 



You take a tablespoon of Calorad® just before you go to sleep and live your normal life. That's it. Could it be any simpler? 



In the first 45 to 90 minutes of sleep your body should enter "Delta Sleep Mode." During this stage, the body repairs and rebuilds itself. Source: David Duhon, M.D./Neurologist It is suggested that you do not eat or drink anything except water for at least three hours before sleep. The body should look for another source of fuel to create the energy required to assist the rebuilding process. Remember, fat is stored energy. When we were young we had faster metabolisms and our bodies used energy to build muscle and bone and to maintain good health while we slept. As we get older, this process slows down. There is nothing complicated about Calorad®.


It works naturally with the body.


It is a ready source of nutrition.

Order Calorad Bovine Formula today On Sale! Save today at Introductory Prices!

Click to buy now Calorad - "The Original" Liquid Collagen - bottle 500ml


Three Studies


These are quotes of studies posted on Pub Med that demonstrate our product Calorad may have a positive effect on health. These are only a few of a multitude of reasons for people to use it!

PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical articles back to the 1950s. PubMed includes links to full text articles and other related resources.

Study #1
The effects of collagen hydrolysat on symptoms of chronic fibromyalgia and temporomandibular joint pain. Olson GB, Savage S, Olson J.; PMID: 11202824 [PubMed - indexed for MEDLINE]

Twenty (20) people who had medically diagnosed fibromyalgia for two to 15+ years participated in and completed a 90-day evaluation to determine effects of collagen hydrolysat on symptoms of chronic fibromyalgia, with twelve reporting temporomandibular joint pain. Collagen hydrolysat is a food supplement that is available without prescription, with no known side effects. Participants were evaluated initially and then at 30-, 60-, and 90-day periods. Final results were obtained and comparisons made. The average pain complaint levels decreased significantly in an overall group average, and dramatically with some individuals. It was concluded that patients with fibromyalgia and concurrent temporomandibular joint problems may gain symptomatic improvement in their chronic symptoms by taking collagen hydrolysat.

Study #2
Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial. Barnett ML, Kremer JM, St Clair EW, Clegg DO, Furst D, Weisman M, Fletcher MJ, Chasan-Taber S, Finger E, Morales A, Le CH, Trentham DE; Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.; PMID: 9485087 [PubMed - indexed for MEDLINE]

OBJECTIVE: Oral administration of cartilage-derived type II collagen (CII) has been shown to ameliorate arthritis in animal models of joint inflammation, and preliminary studies have suggested that this novel therapy is clinically beneficial and safe in patients with rheumatoid arthritis (RA). The present study was undertaken to test the safety and efficacy of 4 different dosages of orally administered CII in patients with RA.

METHODS: Two hundred seventy-four patients with active RA were enrolled at 6 different sites and randomized to receive placebo or 1 of 4 dosages (20, 100, 500, or 2,500 microg/day) of oral CII for 24 weeks. Efficacy parameters were assessed monthly. Cumulative response rates (percentage of patients meeting the criteria for response at any time during the study) were analyzed utilizing 3 sets of composite criteria: the Paulus criteria, the American College of Rheumatology criteria for improvement in RA, and a requirement for > or = 30% reduction in both swollen and tender joint counts.

RESULTS: Eighty-three percent of patients completed 24 weeks of treatment. Numeric trends in favor of the 20 microg/day treatment group were seen with all 3 cumulative composite measures. However, a statistically significant increase (P = 0.035) in response rate for the 20 microg/day group versus placebo was detected using only the Paulus criteria. The presence of serum antibodies to CII at baseline was significantly associated with an increased likelihood of responding to treatment. No treatment-related adverse events were detected. The efficacy seen with the lowest dosage is consistent with the findings of animal studies and with known mechanisms of oral tolerance in which lower doses of orally administered autoantigens preferentially induce disease-suppressing regulatory cells.

CONCLUSION: Positive effects were observed with CII at the lowest dosage tested, and the presence of serum antibodies to CII at baseline may predict response to therapy. No side effects were associated with this novel therapeutic agent. Further controlled studies are required to assess the efficacy of this treatment approach.

Study #3
Role of collagen hydrolysate in bone and joint disease. Moskowitz RW.; Case Western Reserve University, Division of Rheumatic Diseases, University Hospitals of Cleveland, OH, USA.; PMID: 11071580 [PubMed - indexed for MEDLINE]

OBJECTIVES: To review the current status of collagen hydrolysate in the treatment of osteoarthritis and osteoporosis.

METHODS: Review of past and current literature relative to collagen hydrolysate metabolism, and assessment of clinical investigations of therapeutic trials in osteoarthritis and osteoporosis.

RESULTS: Hydrolyzed gelatin products have long been used in pharmaceuticals and foods; these products are generally recognized as safe food products by regulatory agencies. Pharmaceutical-grade collagen hydrolysate (PCH) is obtained by hydrolysis of pharmaceutical gelatin. Clinical studies suggest that the ingestion of 10 g PCH daily reduces pain in patients with osteoarthritis of the knee or hip; blood concentration of hydroxyproline is increased. Clinical use is associated with minimal adverse effects, mainly gastrointestinal, characterized by fullness or unpleasant taste. In a multicenter, randomized, doubleblind, placebo-controlled trial performed in clinics in the United States, United Kingdom, and Germany, results showed no statistically significant differences for the total study group (all sites) for differences of mean pain score for pain. There was, however, a significant treatment advantage of PCH over placebo in German sites. In addition, increased efficacy for PCH as compared to placebo was observed in the overall study population amongst patients with more severe symptomatology at study onset. Preferential accumulation of 14C-labeled gelatin hydrolysate in cartilage as compared with administration of 14C-labeled proline has been reported. This preferential uptake by cartilage suggests that PCH may have a salutary effect on cartilage metabolism. Given the important role for collagen in bone structure, the effect of PCH on bone metabolism in osteoporotic persons has been evaluated. Studies of the effects of calcitonin with and without a collagen hydrolysate-rich diet suggested that calcitonin plus PCH had a greater effect in inhibiting bone collagen breakdown than calcitonin alone, as characterized by a fall in levels of urinary pyridinoline cross-links. PCH appeared to have an additive effect relative to use of calcitonin alone.

CONCLUSIONS: Collagen hydrolysate is of interest as a therapeutic agent of potential utility in the treatment of osteoarthritis and osteoporosis. Its high level of safety makes it attractive as an agent for long-term use in these chronic disorders.

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Calorad Testimonials

Click to read the many testimonials that describe personal experiences from Calorad users like you.

Collagen is currently a very popular subject these days and for good reason. A goodly portion of the human body is collagen. Additionally there are many studies that have been written and continue to be reported on the beneficial value of collagen in its various forms. Try it yourself!

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Click to buy now Calorad - "The Original" Liquid Collagen - bottle 500ml

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DISCLAIMER: Please note none of the statements made on this website have been evaluated or approved by the F.D.A. and no medical claims or claims of cure are being made. As with any alternative nutritional supplement, please consult your physician before taking.

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